Multicomponent dipeptide hydrogels as extracellular matrix-mimetic scaffolds for cell culture applications.
نویسندگان
چکیده
Fmoc-3F-Phe-Arg-NH2 and Fmoc-3F-Phe-Asp-OH dipeptides undergo coassembly to form two-component nanofibril hydrogels. These hydrogels support the viability and growth of NIH 3T3 fibroblast cells. The supramolecular display of Arg and Asp at the nanofibril surface effectively mimics the integrin-binding RGD peptide of fibronectin, without covalent connection between the Arg and Asp functionality.
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ورودعنوان ژورنال:
- Chemical communications
دوره 51 56 شماره
صفحات -
تاریخ انتشار 2015